Top 8 Best Ways To SupportHeart HealthRanked (2026)

Ranked Solutions

Ranked by how much each one actually moves the needle — our SAC Efficacy Score™, explained further down.

1. #1

   Omega-3 (EPA/DHA)

   Supplement

   25-35% triglyceride drop + cardiovascular-event reduction at 2-4 g/day

   8.1/10SAC Efficacy Score™

   • Effect size45%Large
   • Evidence40%Very strong
   • Reliability15%Works for most

   The most-evidenced heart supplement — 25-35% triglyceride reduction and cardiovascular-event data at prescription doses. 2-4 g/day EPA/DHA.

   See the Best Omega-3 Fish Oil →What is Omega-3 (EPA/DHA)?
2. #2

   Berberine

   Supplement

   ~20-25% LDL reduction + better glucose control (30+ RCTs)

   7.4/10SAC Efficacy Score™

   • Effect size45%Moderate
   • Evidence40%Strong
   • Reliability15%Works for many

   A metformin-class metabolic lever that also lowers LDL ~20-25% across 30+ RCTs. 500 mg 2-3x/day with meals.

   See the Best Berberine Supplements →What is Berberine?
3. #3

   Magnesium Glycinate

   Supplement

   modest blood-pressure reduction + rhythm support

   7.0/10SAC Efficacy Score™

   • Effect size45%Moderate
   • Evidence40%Strong
   • Reliability15%Works for many

   Supports healthy blood pressure and steady heart rhythm; deficiency tracks with hypertension. 300-400 mg elemental daily.

   See the Best Magnesium Supplements →What is Magnesium Glycinate?
4. #4

   Krill Oil (EPA/DHA)

   Supplement

   EPA/DHA lower triglycerides + support cardiovascular health; phospholipid form aids tolerance

   ⚑ EPA+DHA per serving is often lower than a dosed fish oil — read the actives

   6.9/10SAC Efficacy Score™

   • Effect size45%Moderate
   • Evidence40%Strong
   • Reliability15%Works for many

   Delivers the same EPA+DHA behind fish oil's cardiovascular benefits in phospholipid form — solid for omega-3 status, but per-serving actives are usually lower than dosed fish oil.

   See the Best Krill Oil Supplements →
5. #5

   Beetroot (Dietary Nitrate)

   Supplement

   ~-4.4 mmHg systolic BP in a 2013 meta-analysis via the nitrate to NO pathway

   ⚑ depends on actual nitrate dose, rarely stated on labels

   6.7/10SAC Efficacy Score™

   • Effect size45%Moderate
   • Evidence40%Strong
   • Reliability15%Specific cases

   The nitrate to nitric-oxide pathway lowers systolic blood pressure by ~4-5 mmHg in pooled RCTs — a real, modest vascular lever, limited by undisclosed label nitrate.

   See the Best Beetroot Supplements →What is Beetroot (Dietary Nitrate)?
6. #6

   Algae Oil (Vegan Omega-3)

   Supplement

   EPA/DHA lower triglycerides + support cardiovascular health

   ⚑ dose-dependent; EPA is often the limiting factor in algae oils

   6.7/10SAC Efficacy Score™

   • Effect size45%Moderate
   • Evidence40%Strong
   • Reliability15%Works for many

   Plant-based DHA/EPA — the same fatty acids behind fish oil's cardiovascular benefits, without the fish. Read the mg: many are DHA-heavy and low in EPA.

   See the Best Algae Oil Omega-3 →What is Algae Oil (Vegan Omega-3)?
7. Coming soonFull guide in progress

   #7

   Aged Garlic Extract

   Supplement

   modest but real blood-pressure reduction (meta-analyses)

   6.3/10SAC Efficacy Score™

   • Effect size45%Modest
   • Evidence40%Moderate
   • Reliability15%Works for many

   Aged garlic extract gives a modest but real blood-pressure reduction in meta-analyses — a gentle add-on. 600-1,200 mg/day.
8. #8

   CoQ10 (Ubiquinol)

   Supplement

   replaces statin-depleted CoQ10, easing myalgia/fatigue; modest BP support

   ⚑ clearest benefit in statin users

   6.1/10SAC Efficacy Score™

   • Effect size45%Modest
   • Evidence40%Moderate
   • Reliability15%Specific cases

   Strongest for statin users, whose endogenous CoQ10 the drug depletes — replacing it eases statin-associated muscle pain and fatigue; broader heart-outcome data is thinner.

   See the Best CoQ10 for Statins →What is CoQ10 (Ubiquinol)?

Our methodology

How every score on this page is calculated — transparent and free to cite.

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