Top 8 Best Niacinamide Serums for Looksmaxxing (2026)
8 picks — ranked by our 50/50 methodology
- #1Best overall (value benchmark)
The Ordinary Niacinamide 10% + Zinc 1%
The Ordinary (DECIEM) · 10% niacinamide + 1% zinc PCA, water-based serum, 30 mlSAC Product Score™ — how it breaks down- Effective concentration (matched to evidence)30%9.2
- Barrier-supporting formula25%8.6
- Tolerability + real-world response20%8.8
- Value (cost per ml / per course)15%9.9
- Formulation extras + finish10%8.4
The bottle the entire category is measured against — 10% niacinamide plus 1% zinc for oil and blemishes, fragrance-free, water-light, and priced at a few dollars. The correct first niacinamide serum for almost everyone.
- Niacinamide
- 10% (a sensible, well-tolerated strength)
- Key support
- 1% zinc PCA (sebum + blemish support)
- Base
- Water-based, fragrance-free, oil-free
- Size
- 30 ml dropper bottle
Pros- 10% niacinamide sits at the top of the sensible range — effective for tone, oil and pores without chasing a needless higher number
- 1% zinc PCA adds real sebum/blemish support that most single-ingredient serums skip
- Fragrance-free, oil-free, water-light — layers cleanly under moisturizer or sunscreen
- The cheapest genuinely-good niacinamide serum on the shelf; the reference product every rival is compared to
Cons- The water-based texture can pill for some people if layered over silicone-heavy products — apply to slightly damp skin, let it absorb
- 10% is a touch strong for the most reactive skin — very sensitive users may prefer to start every other day
- Basic dropper packaging and no soothing extras beyond the zinc
Our take — If you want one niacinamide serum and don't want to overthink it, this is the answer and has been for years. Ten percent is the right strength — high enough to work on oil, tone and pores, not so high it courts irritation — and the 1% zinc is a genuine bonus for blemish-prone skin. It's fragrance-free, it costs about the price of a coffee, and it's the product every other serum on this list is implicitly trying to beat. Apply it to slightly damp skin to avoid pilling, start once daily, and most people never need to spend more. It is the value benchmark for a reason.
- #2Best premium (best-formulated)
Paula's Choice 10% Niacinamide Booster
Paula's Choice · 10% niacinamide + vitamin C + licorice, fragrance-free booster, 20 ml8.9/10SAC Product Score™SAC Product Score™ — how it breaks down- Effective concentration (matched to evidence)30%9.4
- Barrier-supporting formula25%9.2
- Tolerability + real-world response20%9.2
- Value (cost per ml / per course)15%7.4
- Formulation extras + finish10%9.2
The best-formulated serum on the list: a fragrance-free 10% niacinamide booster with vitamin C, licorice and antioxidants on a gentle base you can use neat or mix into your moisturizer. Proof that formula quality beats percentage.
- Niacinamide
- 10% (with supporting brighteners)
- Key support
- Vitamin C + licorice + antioxidants (tone)
- Base
- Fragrance-free, gentle, mixable booster
- Size
- 20 ml (use neat or blend into moisturizer)
Pros- 10% niacinamide paired with vitamin C and licorice — a coherent tone-and-texture formula, and living proof the vitamin C 'conflict' is a myth
- Fragrance-free and notably gentle; the flexible-dose booster format lets sensitive skin dilute it into moisturizer
- Paula's Choice's formulation transparency and QC are among the strongest in mass skincare
- Antioxidant support rounds it into a genuine anti-aging/brightening serum rather than a single-note niacinamide shot
Cons- By far the highest cost-per-ml here — you're paying for the co-formulation and the brand
- Small 20 ml size; used neat it disappears faster than a 30 ml value bottle
- Overkill if you only want plain, cheap niacinamide — #1 or #3 do that for a tenth of the price
Our take — This is what you buy when you want the niacinamide use case done properly instead of just cheaply. The 10% strength is right, but the reason it ranks this high is the base: fragrance-free, gentle, and built with vitamin C and licorice so it actually targets tone and texture as a system. It also quietly settles the biggest myth in the category — niacinamide and vitamin C sit in the same bottle here and work fine. The only real knock is price: it's the most expensive per ml on the list. For a skin-first buyer who values a complete, transparent, sensitive-friendly formula over raw grams, it's the best serum here — just not the best value.
- #3Best budget
The Inkey List Niacinamide
The INKEY List · 10% niacinamide + 1% hyaluronic acid serum, 30 ml8.4/10SAC Product Score™SAC Product Score™ — how it breaks down- Effective concentration (matched to evidence)30%9.0
- Barrier-supporting formula25%8.2
- Tolerability + real-world response20%8.6
- Value (cost per ml / per course)15%9.2
- Formulation extras + finish10%7.2
The other few-dollar benchmark: 10% niacinamide plus 1% hyaluronic acid, so you get oil and pore control with a hydration bump baked in. The best budget serum that also supports the barrier.
- Niacinamide
- 10% (sensible strength)
- Key support
- 1% hyaluronic acid (hydration/barrier)
- Base
- Lightweight, fragrance-free serum
- Size
- 30 ml bottle
Pros- 10% niacinamide plus 1% hyaluronic acid — oil/pore control AND a hydration/barrier bump in one cheap bottle
- The HA base makes it feel more cushioned and less potentially-drying than a bare niacinamide solution
- Fragrance-free, lightweight, layers well; huge Amazon track record and review depth
- Near-benchmark value — a few dollars for a well-rounded, barrier-friendly formula
Cons- No zinc, so slightly less blemish/sebum support than #1 for very oily skin
- 10% is still a touch strong for the most reactive skin — start every other day if needed
- Simple actives panel — great value, not a luxe or antioxidant-loaded formula
Our take — The Inkey List is the budget pick that doesn't feel like a compromise. You get the same sensible 10% niacinamide as the leaders, plus 1% hyaluronic acid that adds hydration and makes the serum gentler on the barrier — which is exactly what you want niacinamide doing. It skips the zinc, so The Ordinary (#1) still edges it for oily, blemish-prone skin, but for a few dollars this is a well-rounded, barrier-friendly serum that most people would be perfectly happy using long-term. If your budget is tight and your skin leans normal-to-dry, this is arguably the smartest buy on the list.
- #4Best simple everyday serum
Good Molecules Niacinamide Serum
Good Molecules · 10% niacinamide brightening serum, fragrance-free, 30 ml8.2/10SAC Product Score™SAC Product Score™ — how it breaks down- Effective concentration (matched to evidence)30%8.6
- Barrier-supporting formula25%8.0
- Tolerability + real-world response20%8.4
- Value (cost per ml / per course)15%9.0
- Formulation extras + finish10%7.2
A clean, no-frills 10% niacinamide serum at a value price — fragrance-free and gentle, the honest everyday option when you just want niacinamide and nothing to fuss over.
- Niacinamide
- 10% (sensible strength)
- Key support
- Minimal, clean supporting formula
- Base
- Fragrance-free, lightweight serum
- Size
- 30 ml bottle
Pros- Straightforward 10% niacinamide at the sensible strength, no gimmicks
- Fragrance-free and gentle — an easy, low-risk daily serum for most skin types
- Strong value; a well-liked, widely-available budget option
- Clean, uncomplicated formula that layers without fuss
Cons- No standout support ingredient (no zinc, no HA headline) — it's plain niacinamide
- Overlaps heavily with #1 and #3 without beating either on their strengths
- Less deep a track record than The Ordinary or Inkey List
Our take — Good Molecules is the dependable, do-the-job everyday serum. It nails the fundamentals — 10% niacinamide, fragrance-free, gentle, cheap — without adding a differentiating hero ingredient, which is why it sits just behind the picks that do (zinc in #1, hyaluronic acid in #3). There's nothing wrong with it, and if it's the one in front of you at a good price it's a perfectly smart buy. But for a deliberate order, #1 gives you zinc and #3 gives you hyaluronic acid for similar money, so this lands as the solid, no-frills alternative rather than the first choice.
- #5Best lightweight texture
Glossier Super Pure
Glossier · Niacinamide + zinc clarifying gel-serum, fragrance-free, 30 ml7.9/10SAC Product Score™SAC Product Score™ — how it breaks down- Effective concentration (matched to evidence)30%8.8
- Barrier-supporting formula25%7.8
- Tolerability + real-world response20%8.8
- Value (cost per ml / per course)15%6.2
- Formulation extras + finish10%7.6
The elegant, lightweight option: niacinamide plus zinc in a fresh gel-serum that sinks in fast and layers invisibly. The nicest texture on the list — for buyers who'll pay for feel and can handle its patchy stock.
- Niacinamide
- Niacinamide (moderate, calming level)
- Key support
- Zinc (sebum + blemish support)
- Base
- Fragrance-free lightweight gel-serum
- Size
- 30 ml bottle
Pros- Niacinamide + zinc for redness and blemish support, in an unusually elegant, fast-absorbing gel texture
- Fragrance-free and pared-back — pleasant to layer and comfortable under makeup
- A calming, moderate strength rather than a maximal one — on-brief for tolerability
- Genuinely nice sensorial experience; a gateway serum for people who hate heavy actives
Cons- Availability is the real issue: Glossier is DTC/Sephora-leaning and its Amazon listing is third-party-fulfilled, so stock and price can be volatile
- Costs several times more per ml than the value leaders for a comparable actives payload
- You're partly paying for texture and brand, not extra efficacy
Our take — Super Pure is the pick for people who bounce off basic niacinamide serums because of how they feel. The niacinamide-plus-zinc combination is sensible and the moderate strength is exactly what the evidence supports, but the reason to choose it is the texture — a fresh gel-serum that absorbs instantly and layers invisibly. The catch is practical: Glossier leans direct-to-consumer, so the Amazon listing is third-party-fulfilled and stock can wobble, and you pay a real premium per ml. If elegant feel matters more than squeezing maximum value, it's worth it; if you just want the actives cheaply, the top four beat it.
- #6Best high-strength (with a caveat)
Naturium Niacinamide Serum 12% Plus Zinc 2%
Naturium · 12% niacinamide + 2% zinc, with hyaluronic acid + vitamin E, 30 ml7.8/10SAC Product Score™SAC Product Score™ — how it breaks down- Effective concentration (matched to evidence)30%6.8
- Barrier-supporting formula25%8.4
- Tolerability + real-world response20%7.4
- Value (cost per ml / per course)15%8.6
- Formulation extras + finish10%8.2
A well-built higher-strength option — 12% niacinamide and 2% zinc, cushioned with hyaluronic acid and vitamin E. It works, but 12% is above the sweet spot, so it's ranked as the considered high-strength pick, not the default.
- Niacinamide
- 12% (above the ~5-10% sweet spot)
- Key support
- 2% zinc + hyaluronic acid + vitamin E
- Base
- Cushioned, fragrance-conscious serum
- Size
- 30 ml bottle
Pros- One of the better-FORMULATED high-strength serums — 2% zinc plus hyaluronic acid and vitamin E cushion the higher niacinamide load
- Strong oil and pore control for genuinely oily, resilient skin that tolerates more
- Good value per ml for a loaded, multi-ingredient formula
- The support ingredients partly offset the irritation risk that comes with 12%
Cons- 12% is above the clinically studied sweet spot — no proven upside over 10%, and a higher chance of tingle, flush or purging
- Not a good starting serum for sensitive or reactive skin — better as a step-up once 10% is tolerated
- The higher number is doing marketing work; the added zinc/HA is what actually earns its place
Our take — Naturium is the honest way to rank a high-strength serum: it's genuinely well-built — 12% niacinamide buffered with 2% zinc, hyaluronic acid and vitamin E — but it's demoted on principle, because 12% is above the sweet spot and buys no proven benefit over 10% while adding irritation risk. For oily, resilient skin that has already made friends with 10% and wants a bit more oil control, it's a sensible step-up and a good value. For everyone else, and for anyone with sensitive skin, the moderate-strength picks above are the smarter call. Buy it as a deliberate upgrade, not as your first niacinamide serum.
- #7Best for dark spots (pigment-focused)
La Roche-Posay Mela B3 Serum
La Roche-Posay · 10% niacinamide + Melasyl dark-spot corrector serum, fragrance-free, 30 ml7.7/10SAC Product Score™SAC Product Score™ — how it breaks down- Effective concentration (matched to evidence)30%8.4
- Barrier-supporting formula25%8.2
- Tolerability + real-world response20%8.2
- Value (cost per ml / per course)15%5.4
- Formulation extras + finish10%8.2
The tone specialist: 10% niacinamide paired with La Roche-Posay's Melasyl pigment-targeting molecule, on a gentle fragrance-free base. The pick if stubborn dark spots are your specific goal — priced and positioned as a treatment, not an everyday value serum.
- Niacinamide
- 10% (sensible strength)
- Key support
- Melasyl (targeted dark-spot molecule)
- Base
- Fragrance-free, gentle, derm-brand formula
- Size
- 30 ml bottle
Pros- Pairs a sensible 10% niacinamide with Melasyl, La Roche-Posay's dedicated pigment-targeting molecule — a genuine dark-spot treatment, not just tone-support marketing
- Fragrance-free and gentle on a well-regarded dermatological-brand base; suitable for sensitive skin despite the targeting actives
- The most focused option here for persistent hyperpigmentation and uneven tone specifically
- Strong brand credibility and formulation pedigree
Cons- Premium price for a 30 ml bottle — you pay for the Melasyl technology and the derm brand, not extra niacinamide
- Pigment-specialized: overkill (and overpriced) if you just want general niacinamide barrier/oil support
- Dark-spot results are slow and require diligent daily sunscreen to show — it's a commitment, not a quick fix
Our take — Mela B3 is the outlier on this list, and that's the point: it isn't really competing to be your everyday niacinamide serum, it's competing to fade dark spots. The 10% niacinamide is sensible, but the reason to buy it is the Melasyl pigment molecule layered on top, which makes it a targeted tone treatment from a serious dermatological brand. It ranks last here only because it's the least suited to the general 'good all-round niacinamide serum' brief — it's pricey and pigment-focused. If uneven tone and stubborn dark spots are specifically what you're solving, it's the most purpose-built pick on the page; pair it with daily SPF and give it months.
- #8Best K-beauty (highest strength)
COSRX The Niacinamide 15 Serum
COSRX · 15% niacinamide + 1% zinc PCA, fragrance-free K-beauty serum, 20 ml7.6/10SAC Product Score™SAC Product Score™ — how it breaks down- Effective concentration (matched to evidence)30%6.2
- Barrier-supporting formula25%8.4
- Tolerability + real-world response20%7.6
- Value (cost per ml / per course)15%8.4
- Formulation extras + finish10%8.2
The highest-strength serum here — 15% niacinamide with 1% zinc, fragrance-free and dermatologist-tested. A capable targeted treatment for oil and pores, but 15% is squarely a 'more is not better' pick, so it sits low by design.
- Niacinamide
- 15% (well above the sweet spot)
- Key support
- 1% zinc PCA (sebum + blemish support)
- Base
- Fragrance-free, paraben-free, derm-tested
- Size
- 20 ml bottle
Pros- Fragrance-free, paraben-free and dermatologist-tested for non-irritation despite the high strength
- 1% zinc PCA supports the oil/blemish use case; a focused pore-and-sebum treatment
- A well-known, well-reviewed K-beauty option for skin that specifically wants maximum niacinamide
- Sensible base formulation that partly tames the 15% load
Cons- 15% is the highest here and above every dose in the clinical literature — no proven added benefit over 10%, and the greatest sting/flush/purge risk on the list
- Emphatically not a beginner or sensitive-skin serum — this is a step-up treatment only
- Small 20 ml bottle; higher effective cost per use than the 30 ml value leaders
Our take — COSRX makes a good serum and formulates it responsibly — fragrance-free, zinc-supported, derm-tested — which is the only reason a 15% niacinamide product ranks respectably rather than last. But the strength is exactly what the whole guide argues against: 15% sits above every concentration in the research, offers no proven upside over 10%, and carries the highest irritation risk here. It earns its spot as the deliberate, eyes-open K-beauty pick for resilient skin that specifically wants maximum niacinamide and has already tolerated lower strengths. If you're not chasing the highest number on purpose, the moderate-strength serums above are the better and safer buy.
▸ Affiliate disclosure: every Amazon link uses our Associates tag (superachieverclub-20). We earn a small commission at no cost to you; it funds independent reviews. We never accept payment to change a ranking.
Niacinamide is the active most dermatologists would hand a nervous beginner first, and for good reason: it supports the skin barrier, calms redness, dials down oil, softens the look of enlarged pores, and gently evens tone — and it does all of that while being one of the best-tolerated ingredients on the shelf. That's the whole appeal. It's the low-drama workhorse you can use morning and night, layer under almost anything, and actually stick with. Which is exactly why "best niacinamide serum" is one of the most-searched skincare terms there is, and why the shelf is now a wall of near-identical bottles shouting different percentages at you. That percentage is where nearly everyone goes wrong. The number on the front is not a quality score. The clinical research that built niacinamide's reputation used modest concentrations: the landmark Bissett 2005 study got real reductions in fine lines, dark spots, redness and sallowness using 5% niacinamide; Draelos 2006 cut facial oil with just 2%. Somewhere around 4-5% is the studied sweet spot. Ten percent — the most common retail strength — works fine for most people. But climbing to 12%, 15% or higher does not buy proportionally better skin; it mostly buys a higher chance of stinging, transient flushing, or breakouts in sensitive skin. A well-formulated 5-10% serum on a barrier-supporting base will out-perform a raw 15% serum for the average buyer, every time. So we bought eight of the most-recommended niacinamide serums on Amazon and ranked them on what actually matters: an effective concentration that matches the evidence (not the biggest number), a barrier-supporting formula (added zinc, hyaluronic acid, a soothing base, and ideally fragrance-free), real-world tolerability, and honest value. Two myths get retired along the way. First, higher percentage is not better — if your skin is sensitive, start low. Second, the old "never mix niacinamide with vitamin C" warning is outdated: it came from raw-ingredient and heat conditions decades ago, not from finished modern serums, and in real formulas the two are perfectly fine layered together. Buy niacinamide for a calmer, more even, better-behaved complexion — and let the label number be the last thing you look at, not the first.
Want one bottle that just works and costs almost nothing: The Ordinary Niacinamide 10% + Zinc 1% (#1) is the value benchmark the whole category is measured against — 10% niacinamide, zinc for oil, fragrance-free, a few dollars. Want the single best-FORMULATED serum and will pay a bit more: Paula's Choice 10% Niacinamide Booster (#2), fragrance-free with antioxidants and a genuinely gentle base you can mix into your moisturizer. Tightest budget with a barrier-support bonus: The Inkey List Niacinamide (#3), 10% niacinamide plus 1% hyaluronic acid for a few dollars. Simplest everyday pick: Good Molecules Niacinamide (#4). A lighter, more elegant texture: Glossier Super Pure (#5), niacinamide + zinc in a gel-serum (watch its stock — it's DTC-leaning). Then the honest caveats: Naturium 12% (#6) and COSRX 15% (#7) crank the concentration higher — they work, but higher is NOT better, and both carry more sting/flush risk, so they're demoted, not crowned. And if your real goal is stubborn dark spots specifically, La Roche-Posay Mela B3 (#8) pairs 10% niacinamide with Melasyl for tone — pricey and pigment-focused rather than an everyday barrier serum. Whatever you pick: start once daily, and ignore anyone who tells you it can't share a routine with vitamin C.
How we ranked these eight
Niacinamide is easy to rank badly — just sort by the percentage on the label — and that produces exactly the wrong order, because the evidence rewards moderate strengths, not maximal ones. So effective concentration carries the most weight, but it's scored against the clinical sweet spot (roughly 5-10%), not "more is better": Bissett 2005 used 5%, Draelos 2006 used 2%, and both got results, so a clean 10% serum earns full marks while a raw 15% serum gets no bonus for the extra number and a small penalty for the irritation it invites. Barrier-supporting formula is next — added zinc, hyaluronic acid, a soothing base, no denatured alcohol high on the ingredient list, and fragrance-free where possible — because niacinamide's whole job is to strengthen and calm skin, and a stripping base undercuts that. Tolerability and real-world response measure sting, flush, purging risk and how well the serum plays with other actives, which is where the highest-percentage products lose ground. Value is cost per ml at a realistic once-or-twice-daily use. Formulation extras and finish — texture, pilling resistance, layering, and how transparent the brand is about the actual actives — settle ties.
- Effective concentration (matched to evidence)30%
Scored against the studied sweet spot, not the biggest number. Bissett 2005 used 5% and Draelos 2006 used 2%, so ~5-10% earns full marks; a clean 10% is ideal for most skin. Serums at 12-15%+ get NO bonus for the extra percentage and a small penalty, because above ~10% the benefit curve flattens while irritation risk climbs.
- Barrier-supporting formula25%
Added zinc (oil/blemish support), hyaluronic acid (hydration), a soothing/ceramide-friendly base, no denatured alcohol high on the INCI list, and fragrance-free where possible. Niacinamide's core job is to strengthen and calm the barrier, so the base matters almost as much as the active. Stripping or heavily fragranced formulas lose points.
- Tolerability + real-world response20%
How gentle it actually is: low sting, no persistent flush/tingle, minimal purging, and how well it layers with other actives (including vitamin C — that pairing is fine). Suitability for sensitive skin and beginners is rewarded here, which is exactly where the highest-strength serums slip.
- Value (cost per ml / per course)15%
Price divided by a realistic once-or-twice-daily use over a bottle. Niacinamide is a category where excellent serums cost a few dollars, so a premium price has to be justified by formulation, not brand alone. Tiebreaker within a strength tier.
- Formulation extras + finish10%
Texture, pilling/pill-resistance under makeup, how cleanly it layers, and how transparent the brand is about the real actives panel (not just marketing percentages). Elegant, fast-absorbing, honest formulas settle ties at the top.
The bottom line
If you just want to be told what to buy: get The Ordinary Niacinamide 10% + Zinc 1% (#1). It's the value benchmark for the whole category — 10% niacinamide at the sensible strength, 1% zinc for oil and blemishes, fragrance-free, and a few dollars. For most people that is the entire decision. Want the best-formulated serum and willing to pay for a gentle, antioxidant-backed base you can mix into moisturizer: Paula's Choice 10% Niacinamide Booster (#2). Tightest budget with a hydration bonus: The Inkey List Niacinamide (#3). A plain, reliable everyday serum: Good Molecules (#4). The nicest texture, if you'll tolerate patchy Amazon stock: Glossier Super Pure (#5).
The most important idea in this guide is what NOT to do: don't buy on the percentage. The evidence that made niacinamide famous used modest strengths — Bissett 2005 got real results at 5%, Draelos 2006 cut oil at 2% — and roughly 4-5% is the studied sweet spot, with 10% the sensible retail ceiling for most skin. That's why Naturium 12% (#6) and COSRX 15% (#7), despite both being well-made serums, are ranked below the moderate-strength picks rather than above them: the extra percentage buys no proven benefit over 10% and adds real irritation, flushing and purging risk. They're deliberate step-ups for resilient, oily skin that has already tolerated 10% — not first serums, and definitely not for sensitive skin. And if your actual goal is fading stubborn dark spots rather than general skin support, La Roche-Posay Mela B3 (#8) is the purpose-built tone treatment, just priced and positioned as a specialist rather than an everyday value.
Two honest truths to close. First, niacinamide is one of the best-tolerated actives you can use — barrier-supporting, redness-calming, oil-regulating and tone-evening — which is exactly why it makes such a good first active and why a well-formulated moderate-strength serum beats a raw high-percentage one for almost everyone. Start once daily, build up, and if your skin is sensitive, start low on purpose. Second, ignore the tired warning that you can't use niacinamide with vitamin C: that myth comes from decades-old raw-ingredient and heat conditions, not from finished modern serums — Paula's Choice (#2) literally puts both in one bottle — so layer them together without a second thought. Buy for a calmer, more even, better-behaved complexion, dose it sensibly, and let the label number be the last thing you look at.
Every claim ranked above traces back to one of these
Peer-reviewed studies, meta-analyses and clinical trials behind the picks. Click any citation to read the abstract on PubMed.
- [1]Bissett 2005
Niacinamide: A B vitamin that improves aging facial skin appearance
In a 12-week double-blind, split-face study, 5% topical niacinamide applied twice daily significantly reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness versus its vehicle control. The anchor trial for niacinamide's tone-and-texture benefits and the key evidence that a MODERATE ~5% concentration is clinically effective — the basis for rewarding sensible-strength serums over the highest label number.
- [2]Draelos 2006
The effect of 2% niacinamide on facial sebum production
Topical 2% niacinamide reduced facial sebum excretion rate and casual sebum levels over 4-6 weeks in clinical testing. The reference for niacinamide's oil/sebum-control use case, and further evidence that low concentrations are biologically active — reinforcing that chasing 12-15%+ is unnecessary for the sebum and pore benefits most buyers want.
- [3]Hakozaki 2002
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Niacinamide inhibited melanosome transfer from melanocytes to keratinocytes (35-68% inhibition in a coculture model) and significantly decreased hyperpigmentation while increasing skin lightness versus vehicle in a clinical study. The mechanistic basis for niacinamide's tone-evening and dark-spot benefits and the rationale behind the pigment-focused pick (La Roche-Posay Mela B3, #8).
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