Top 9 Best Black Cohosh Supplements (2026)

Updated Jul 13, 2026By Felix Hesse9 products analyzed6 peer-reviewed sourcesAffiliate links

Remifemin Menopause Symptoms Relief, 120 Tablets01 · Clinical Gold Standard✓ Label verified · Supplement Facts read Sep 7, 2026
The One To Buy

Clinical Gold Standard: Remifemin Menopause Symptoms Relief, 120 Tablets

This is the specific isopropanolic extract behind the majority of black cohosh menopause trials. If any black cohosh has a shot at working for your hot flashes, it is the one the researchers actually put in the bottle.

7.9SAC Product Score™
StrongestStandardization & Form8.51
WeakestValue6.5

~$33.99~$1.13/day (4 tablets at 2 twice daily)

Why it wins: all five scores, pros & cons, full label
Standardization & Form30%8.51
Third-Party Testing & Purity25%8.02
Dose vs Clinical Range20%8.01
Tolerability & Safety15%7.52
Value10%6.5
What We Like
  • The single most clinically studied black cohosh extract (used across 35+ trials), so its results are the ones the evidence base is built on
  • Standardized isopropanolic extract with a fixed triterpene-glycoside content, not a guess-what-you-get whole-root powder
  • Label dose exactly matches the 20 mg twice-daily regimen used in research
  • Estrogen-free and made under German pharmaceutical manufacturing standards
What You Live With
  • Most expensive per day on this list, and a 120-count is only about a month at full dose
  • Even the best-studied extract shows mixed results vs placebo, and it still carries the class hepatotoxicity caution
Standardization
~1 mg triterpene glycosides (27-deoxyactein) per tablet
Cost per dose
~$1.13 per day
Dose
20 mg extract per tablet; label dose 2 tablets twice daily
Form
Tablet (isopropanolic standardized extract)
Count
120 tablets (~30-day supply at label dose)
Testing
German pharmaceutical-grade manufacture; estrogen-free

Our take — If you are going to try black cohosh, start with the extract the studies actually used rather than a cheaper substitute hoping it behaves the same. Remifemin earns the top spot on standardization and dose fidelity, not price. Give it 8-12 weeks, track your hot flashes honestly, and stop at any sign of liver trouble (dark urine, jaundice, right-upper-abdominal pain).

Or Pick By What Matters To You
Compare All 9

Who Wins Which Aspect

Rank By

Sorted by overall SAC Product Score™ — the official ranking.

All 9 picks side by side — one column per scoring criterion, gold marks the best value in a column.
#PickScoreStandardization & Form30%Third-Party Testing & Purity25%Dose vs Clinical Range20%Tolerability & Safety15%Value10%Cost Per DoseBuy
01
RemifeminClinical Gold Standard8.58.08.07.56.5
7.98.518.028.017.526.5~$1.13 / dayCheck price
The single most clinically studied black cohosh extract (used across 35+ trials), so its results are the ones the evidence base is built onMost expensive per day on this list, and a 120-count is only about a month at full dose
02
Natural Factors WomenSenseBest Third-Party Tested8.09.06.08.07.0
7.88.029.016.038.017.03~$0.20-0.40 / dayCheck price
Isura third-party testing for identity and purity is the strongest verification on this list, and it directly counters black cohosh adulteration with cheaper Asian speciesAt 40 mg per capsule you likely need two daily to reach the studied dose, which shortens the 90-count
03
Source NaturalsBest Standardized Value8.05.07.07.58.5
7.08.025.07.027.528.51~$0.14 / tabletCheck price
Delivers a full ~2 mg triterpene-glycoside dose per tablet, at or above the studied daily rangeNo explicit independent third-party seal (relies on the brand's own standardization claim)
04
NOW + Licorice & Dong QuaiCheapest Standardized8.06.06.05.58.5
6.88.026.06.035.58.51~$0.12 / capsuleCheck price
Standardized to 2.5% triterpene glycosides at a full ~2 mg per capsuleAdded licorice (can raise blood pressure and lower potassium) and dong quai (anticoagulant effects, photosensitivity) introduce their own risks and interactions
05
Gaia Herbs Phyto-CapsBest Organic Single-Herb Liquid5.06.57.07.56.0
6.35.036.57.027.526.0~$0.40 / capsuleCheck price
Certified USDA Organic Actaea racemosa root in a clean single-herb formulaLists root strength, not a guaranteed triterpene-glycoside content, so actives per capsule are not pinned down
06
Nature's Way Root 540 mgBest DNA-Authenticated Whole Root4.07.56.06.57.0
6.04.07.536.036.57.03~$0.09 / servingCheck price
TRU-ID DNA authentication confirms the plant is genuine Actaea racemosa, directly addressing the species-adulteration riskWhole-root powder is not standardized, so the active triterpene-glycoside content is unknown and varies batch to batch
07
Zazzee Organic 10:1Best Organic Concentrate4.56.06.06.06.5
5.64.56.06.036.06.5~$0.18 / capsuleCheck price
USDA Organic and Non-GMO with a clean pullulan capsule and no fillersA 10:1 ratio describes concentration, not active content, so triterpene glycosides per capsule are still unspecified
08
Nature's Bounty 540 mgMainstream Budget Pick4.05.06.06.08.0
5.44.05.06.036.08.02~$0.11 / capsuleCheck price
Very low cost and available almost everywhere, an easy entry pointNot standardized, so active triterpene content is unknown and inconsistent between batches
09
Black Cohosh GummiesSkip: Weakest Actives3.55.55.07.06.5
5.13.55.55.07.036.5~$0.33 / gummyCheck price
Easy chewable format for anyone who cannot or will not swallow pillsJust 50 mg of unstandardized root is the weakest actives-per-serving here, well below the doses studied for hot flashes
The Ranked List

The Other 8, Ranked

  1. Natural Factors WomenSense Black Cohosh Extract 40 mg, 90 Vegetarian Capsules02

    Best Third-Party Tested: Natural Factors WomenSense Black Cohosh Extract 40 mg, 90 Vegetarian Capsules

    7.8SAC Score™

    The best-tested standardized extract here. Its Isura third-party program directly answers black cohosh's biggest quality risk: species adulteration.

    StrongestThird-Party Testing & Purity9.01
    WeakestDose vs Clinical Range6.0
    Standardization
    2.5% triterpene glycosides (1 mg 27-deoxyacteine per capsule)
    Cost per dose
    ~$0.20-0.40 per day
    Dose
    40 mg extract per capsule; once to twice daily
    All five scores, pros & cons, full label
    Standardization & Form30%8.02
    Third-Party Testing & Purity25%9.01
    Dose vs Clinical Range20%6.03
    Tolerability & Safety15%8.01
    Value10%7.03
    What We Like
    • Isura third-party testing for identity and purity is the strongest verification on this list, and it directly counters black cohosh adulteration with cheaper Asian species
    • Standardized to 2.5% triterpene glycosides, so you know the active content per capsule
    • Clean single-herb vegetarian formula with explicit liver-caution labeling
    • Sensible per-day cost for a premium standardized extract
    What You Live With
    • At 40 mg per capsule you likely need two daily to reach the studied dose, which shortens the 90-count
    • Like all black cohosh, benefit vs placebo is not guaranteed and the hepatotoxicity signal still applies
    Form
    Vegetarian capsule (standardized extract)
    Count
    90 vegetarian capsules
    Testing
    Isura in-house third-party testing for identity and purity

    Our take — This is the pick for anyone who wants a standardized extract with real independent verification behind it. It loses to Remifemin only on dose fidelity and the depth of trial evidence tied to the isopropanolic form. For quality-obsessed buyers, the Isura testing makes it the smartest runner-up.

  2. Source Naturals Black Cohosh Extract, 120 Tablets03

    Best Standardized Value: Source Naturals Black Cohosh Extract, 120 Tablets

    7.0SAC Score™

    A full-dose standardized extract at a low per-tablet cost. Single-herb, 2.5% triterpene glycosides, and a long 120-count supply.

    StrongestValue8.51
    WeakestThird-Party Testing & Purity5.0
    Standardization
    2.5% triterpene glycosides (~2 mg per tablet)
    Cost per dose
    ~$0.14 per tablet
    Dose
    80 mg extract per tablet
    All five scores, pros & cons, full label
    Standardization & Form30%8.02
    Third-Party Testing & Purity25%5.0
    Dose vs Clinical Range20%7.02
    Tolerability & Safety15%7.52
    Value10%8.51
    What We Like
    • Delivers a full ~2 mg triterpene-glycoside dose per tablet, at or above the studied daily range
    • Standardized to 2.5% triterpene glycosides for consistent actives, not raw powder
    • 120-count tablet size gives a long supply at one of the lowest per-dose costs for a standardized extract
    • Single-herb formula keeps the effect attributable to black cohosh alone
    What You Live With
    • No explicit independent third-party seal (relies on the brand's own standardization claim)
    • Hot-flash relief vs placebo remains inconsistent across trials, and liver caution applies
    Form
    Tablet (standardized extract)
    Count
    120 tablets
    Testing
    Standardized extract; made in USA (brand quality program)

    Our take — The value standout among genuinely standardized options: you get a full clinical-range dose per tablet without paying premium pricing. It ranks below Natural Factors purely because it lacks a named independent testing program. For a budget-conscious buyer who still insists on standardization, this is the one.

  3. NOW Supplements Black Cohosh Root 80 mg with Licorice and Dong Quai, 90 Veg Capsules04

    Cheapest Standardized (with caveats): NOW Supplements Black Cohosh Root 80 mg with Licorice and Dong Quai, 90 Veg Capsules

    6.8SAC Score™

    A standardized 80 mg extract at the lowest price here, but it bundles licorice and dong quai, so you cannot credit or blame black cohosh alone.

    StrongestValue8.51
    WeakestTolerability & Safety5.5
    Standardization
    2.5% triterpene glycosides (2 mg 27-deoxyactein)
    Cost per dose
    ~$0.12 per capsule
    Dose
    80 mg extract; 1 capsule twice daily
    All five scores, pros & cons, full label
    Standardization & Form30%8.02
    Third-Party Testing & Purity25%6.0
    Dose vs Clinical Range20%6.03
    Tolerability & Safety15%5.5
    Value10%8.51
    What We Like
    • Standardized to 2.5% triterpene glycosides at a full ~2 mg per capsule
    • Lowest cost per dose of any standardized product on the list
    • GMP Quality Assured, Non-GMO, and vegetarian from a well-regarded manufacturer
    What You Live With
    • Added licorice (can raise blood pressure and lower potassium) and dong quai (anticoagulant effects, photosensitivity) introduce their own risks and interactions
    • The multi-botanical blend means any benefit or side effect cannot be attributed to black cohosh alone, which muddies both efficacy and safety
    Form
    Capsule (standardized extract + added botanicals)
    Count
    90 veg capsules
    Testing
    GMP Quality Assured; Non-GMO; vegetarian

    Our take — A legitimately cheap standardized extract, but the added licorice and dong quai drop it below the clean single-herb options on safety and interpretability. If you specifically want a traditional multi-herb menopause blend and have no blood-pressure or bleeding concerns, it is a strong value; if you want to know what black cohosh alone does, choose a single-herb pick above.

  4. Gaia Herbs Black Cohosh, 60 Vegan Liquid Phyto-Caps05

    Best Organic Single-Herb Liquid: Gaia Herbs Black Cohosh, 60 Vegan Liquid Phyto-Caps

    6.3SAC Score™

    A clean, certified-organic single-herb liquid extract with strong traceability, but it lists root strength rather than a guaranteed triterpene-glycoside percentage.

    StrongestTolerability & Safety7.52
    WeakestStandardization & Form5.0
    Standardization
    Not standardized to a fixed triterpene-glycoside percentage
    Cost per dose
    ~$0.40 per capsule
    Dose
    ~400 mg organic root extract per capsule
    All five scores, pros & cons, full label
    Standardization & Form30%5.03
    Third-Party Testing & Purity25%6.5
    Dose vs Clinical Range20%7.02
    Tolerability & Safety15%7.52
    Value10%6.0
    What We Like
    • Certified USDA Organic Actaea racemosa root in a clean single-herb formula
    • Liquid extract sealed in a vegan capsule disperses faster than a dry powder
    • Strong ingredient traceability and clean allergen profile (soy-free, gluten-free, vegan)
    What You Live With
    • Lists root strength, not a guaranteed triterpene-glycoside content, so actives per capsule are not pinned down
    • Higher cost than several standardized extracts despite less certainty about the dose you receive
    Form
    Liquid phyto-cap (liquid extract in a vegan capsule)
    Count
    60 liquid phyto-caps
    Testing
    USDA Organic root; Gaia traceability program; vegan, soy- and gluten-free

    Our take — The best choice if organic sourcing and a clean single-herb liquid matter most to you. It ranks mid-pack because without a standardized triterpene percentage you cannot confirm you are hitting the studied dose. Good provenance, less dosing certainty than the extracts above.

  5. Nature's Way Black Cohosh Root, 540 mg per Serving, 180 Vegan Capsules06

    Best DNA-Authenticated Whole Root: Nature's Way Black Cohosh Root, 540 mg per Serving, 180 Vegan Capsules

    6.0SAC Score™

    TRU-ID DNA-authenticated whole root at a great per-serving price, so you know it is real black cohosh, even if you do not know its active potency.

    StrongestThird-Party Testing & Purity7.53
    WeakestStandardization & Form4.0
    Standardization
    None (whole-root powder, triterpene content varies by batch)
    Cost per dose
    ~$0.09 per serving
    Dose
    540 mg whole root per serving
    All five scores, pros & cons, full label
    Standardization & Form30%4.0
    Third-Party Testing & Purity25%7.53
    Dose vs Clinical Range20%6.03
    Tolerability & Safety15%6.5
    Value10%7.03
    What We Like
    • TRU-ID DNA authentication confirms the plant is genuine Actaea racemosa, directly addressing the species-adulteration risk
    • Non-GMO Project Verified and vegan
    • Excellent value: 180 servings at roughly nine cents each
    What You Live With
    • Whole-root powder is not standardized, so the active triterpene-glycoside content is unknown and varies batch to batch
    • You cannot reliably match the standardized-extract doses used in the trials that showed benefit
    Form
    Vegan capsule (whole root powder)
    Count
    180 vegan capsules
    Testing
    Non-GMO Project Verified; TRU-ID DNA authenticated

    Our take — If you prefer whole root over an extract and want proof it is authentic black cohosh, this is the pick, and the price is hard to beat. It ranks below the standardized extracts because DNA authentication tells you what the plant is, not how potent it is. Verified identity, unverified potency.

  6. Zazzee USDA Organic Black Cohosh 10:1 Extract, 120 Vegan Capsules07

    Best Organic Concentrate: Zazzee USDA Organic Black Cohosh 10:1 Extract, 120 Vegan Capsules

    5.6SAC Score™

    A USDA Organic 10:1 concentrate with a long four-month supply, but concentration by ratio is not the same as standardization to a known active content.

    StrongestValue6.5
    WeakestStandardization & Form4.5
    Standardization
    Concentrated 10:1 by ratio; not standardized to a fixed triterpene percentage
    Cost per dose
    ~$0.18 per capsule
    Dose
    300 mg of 10:1 extract (3000 mg root equivalent) per capsule, 1 daily
    All five scores, pros & cons, full label
    Standardization & Form30%4.5
    Third-Party Testing & Purity25%6.0
    Dose vs Clinical Range20%6.03
    Tolerability & Safety15%6.0
    Value10%6.5
    What We Like
    • USDA Organic and Non-GMO with a clean pullulan capsule and no fillers
    • 10:1 concentration delivers a high root-equivalent per capsule
    • Four-month supply at one capsule daily is convenient and economical
    What You Live With
    • A 10:1 ratio describes concentration, not active content, so triterpene glycosides per capsule are still unspecified
    • Once-daily dosing may not mirror the split twice-daily regimens used in the trials
    Form
    Vegan capsule (10:1 concentrated extract)
    Count
    120 vegan capsules (~4-month supply)
    Testing
    USDA Organic; Non-GMO; made in USA

    Our take — A reasonable organic concentrate for buyers who want a strong root-equivalent and a long supply. It lands in the lower half because ratio-concentration without a standardized triterpene figure leaves the actual active dose unconfirmed. Concentrated, but not characterized.

  7. Nature's Bounty Black Cohosh Root, 540 mg, 100 Capsules08

    Mainstream Budget Pick: Nature's Bounty Black Cohosh Root, 540 mg, 100 Capsules

    5.4SAC Score™

    A cheap, widely available whole-root capsule from a mainstream brand, fine as a basic try, but unstandardized and only brand-lab tested.

    StrongestValue8.02
    WeakestStandardization & Form4.0
    Standardization
    None (not standardized to triterpene glycosides)
    Cost per dose
    ~$0.11 per capsule
    Dose
    540 mg whole root per capsule, 1 daily
    All five scores, pros & cons, full label
    Standardization & Form30%4.0
    Third-Party Testing & Purity25%5.0
    Dose vs Clinical Range20%6.03
    Tolerability & Safety15%6.0
    Value10%8.02
    What We Like
    • Very low cost and available almost everywhere, an easy entry point
    • 540 mg whole-root dose in a simple one-a-day capsule
    • Backed by a large mainstream brand's internal quality program
    What You Live With
    • Not standardized, so active triterpene content is unknown and inconsistent between batches
    • Only brand-level 'lab tested' with no independent third-party or DNA authentication, and the hepatotoxicity caution still applies
    Form
    Capsule (whole root powder)
    Count
    100 capsules
    Testing
    Laboratory tested (brand quality program only)

    Our take — The definition of a mainstream budget option: convenient and inexpensive, but unstandardized and lacking any independent verification. It sits near the bottom because you cannot confirm either the plant identity or the active dose. Buy it for accessibility, not for precision.

  8. Black Cohosh Gummies for Menopause Relief, 50 mg, 60 Gummies09

    Skip: Weakest Actives: Peach-flavor Black Cohosh Gummies Black Cohosh Gummies for Menopause Relief, 50 mg, 60 Gummies

    5.1SAC Score™

    A pleasant peach chewable, but at 50 mg of unstandardized root with added sugar, it delivers the least active compound per serving on this list.

    StrongestTolerability & Safety7.03
    WeakestStandardization & Form3.5
    Standardization
    None (unstandardized root, no triterpene figure)
    Cost per dose
    ~$0.33 per gummy
    Dose
    50 mg whole root per serving
    All five scores, pros & cons, full label
    Standardization & Form30%3.5
    Third-Party Testing & Purity25%5.5
    Dose vs Clinical Range20%5.0
    Tolerability & Safety15%7.03
    Value10%6.5
    What We Like
    • Easy chewable format for anyone who cannot or will not swallow pills
    • Peach flavor, gluten-free, vegetarian, and Non-GMO
    • Generally well tolerated as a gentle, low-dose introduction
    What You Live With
    • Just 50 mg of unstandardized root is the weakest actives-per-serving here, well below the doses studied for hot flashes
    • Added sugar and no standardization or independent testing make it the least evidence-aligned option
    Form
    Gummy (chewable, added sugar)
    Count
    60 gummies
    Testing
    Gluten-free, vegetarian, Non-GMO claims (no third-party seal)

    Our take — The gummy wins on palatability and nothing else. Its 50 mg unstandardized dose with added sugar is unlikely to replicate the clinical extracts, so it ranks last on the axes that predict a real effect. Choose it only if a chewable is the sole way you will take anything, and expect the least.

Buying Guide

Black Cohosh In Two Short Lessons

RULE 1

Avoid it with liver disease, and watch for warning signs.

Rare cases of liver injury have been documented. Stop immediately if jaundice, dark urine or right-upper-abdominal pain appears.

RULE 2

Choose a standardized extract.

The studies that show benefit used standardized extracts, not raw root. Black cohosh is not a classic phytoestrogen, so ignore vague 'natural hormone support' labels.

RULE 3

Keep expectations realistic.

The 2012 Cochrane review found insufficient evidence for menopausal symptoms, and high-quality trials often failed to separate it from placebo on hot flashes.

Synthesized from the Cochrane Database of Systematic Reviews (Leach & Moore, 2012), the NIH-funded HALT trial (Newton et al., Annals of Internal Medicine, 2006), and hepatotoxicity causality reviews (Teschke, Menopause, 2010).

Verdict

The bottom line

01

Buy the extract the studies used: Remifemin wins

The isopropanolic Remifemin extract is the specific preparation behind most of the positive black cohosh trials, and it matches the exact 20 mg twice-daily dose researchers used. It costs the most per day, but standardization and dose fidelity, not price, put it at #1. If you are going to try black cohosh at all, start with the version the evidence base is actually built on.

02

For testing obsessives, Natural Factors is the smartest pick

Black cohosh is a documented adulteration target, so independent verification is worth real weight. Natural Factors WomenSense pairs a 2.5%-standardized extract with the Isura third-party program, giving you the strongest identity-and-purity assurance on the list. It is the runner-up only because the isopropanolic form carries deeper trial evidence.

03

Standardization beats price, and whole-root powders sit below extracts

Source Naturals proves you can get a full clinical-range standardized dose cheaply, so budget buyers do not have to drop to raw powder. Whole-root capsules and gummies (Nature's Way, Nature's Bounty, the peach gummy) rank lower not because they are fake, but because unstandardized root leaves the active triterpene content, and thus your odds of matching the studied dose, unknown.

Frequently Asked

Quick Answers

What is the best black cohosh pick overall?

Remifemin Menopause Symptoms Relief, 120 Tablets by Remifemin is our #1 pick (SAC score 7.9/10). If you are going to try black cohosh, start with the extract the studies actually used rather than a cheaper substitute hoping it behaves the same. Remifemin earns the top spot on standardization and dose fidelity, not price. Give it 8-12 weeks, track your hot flashes honestly, and stop at any sign of liver trouble (dark urine, jaundice, right-upper-abdominal pain).

What is the best budget option?

Source Naturals Black Cohosh Extract, 120 Tablets at ~$16.50. The value standout among genuinely standardized options: you get a full clinical-range dose per tablet without paying premium pricing. It ranks below Natural Factors purely because it lacks a named independent testing program. For a budget-conscious buyer who still insists on standardization, this is the one.

How much do these picks cost?

Across our ranked picks, prices run from about $10.99 to $33.99 — exact price and cost per serving are listed on every pick card above.

How were these picks ranked?

Black cohosh (Actaea/Cimicifuga racemosa) works through mechanisms that are still debated, and it does not measurably raise estrogen the way soy isoflavones can, so extract quality matters more here than in almost any other menopause supplement. We weighted the five axes below to reward the standardized extracts that clinical trials actually tested, penalize unstandardized whole-root powders where the active triterpene-glycoside content is unknown batch to batch, and dock products that muddy the picture with added botanicals or sub-clinical doses. Quality drives the ranking; price is capped at 10% and can only ever break a tie, never buy a spot at the top. We hold every product to the same honesty bar: black cohosh carries a rare hepatotoxicity signal, and no formulation is exempt.

Research & Sources

Every Claim Ranked Above Traces Back To One Of These

6 peer-reviewed sources, each linked to PubMed
  1. [1] Leach MJ, Moore V. Black cohosh (Cimicifuga spp.) for menopausal symptoms. Cochrane Database of Systematic Reviews. 2012;(9):CD007244. PMID 22972105 — Black cohosh (Cimicifuga spp.) for menopausal symptoms. Systematic review found insufficient evidence to support the use of black cohosh for menopausal symptoms, with trials showing no consistent significant difference from placebo on hot flashes.
  2. [2] Newton KM, Reed SD, LaCroix AZ, et al. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Annals of Internal Medicine. 2006;145(12):869-879. PMID 17179056 — Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial (HALT study). In this NIH-funded randomized trial, black cohosh (alone or in a multibotanical) did not reduce vasomotor symptoms more than placebo over 12 months.
  3. [3] Wuttke W, Seidlova-Wuttke D, Gorkow C. The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study: effects on menopause symptoms and bone markers. Maturitas. 2003;44 Suppl 1:S67-S77. PMID 12609561 — The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study: effects on menopause symptoms and bone markers. A standardized black cohosh extract improved climacteric complaints comparably to conjugated estrogens versus placebo, without an estrogenic effect on the endometrium, supporting a non-classically-estrogenic mechanism.
  4. [4] Osmers R, Friede M, Liske E, Schnitker J, Freudenstein J, Henneicke-von Zepelin HH. Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms. Obstetrics & Gynecology. 2005;105(5 Pt 1):1074-1083. PMID 15863547 — Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms. A randomized, double-blind, placebo-controlled trial of the isopropanolic black cohosh extract (the Remifemin form) reported a significant reduction in climacteric symptoms versus placebo with good tolerability.
  5. [5] Teschke R. Black cohosh and suspected hepatotoxicity: inconsistencies, confounding variables, and prospective use of a diagnostic causality algorithm. A critical review. Menopause. 2010;17(2):426-440. PMID 20216279 — Black cohosh and suspected hepatotoxicity: inconsistencies, confounding variables, and prospective use of a diagnostic causality algorithm. A critical review. Critical review of reported black cohosh liver-injury cases found causality often weak or confounded, but concluded a rare hepatotoxicity signal cannot be excluded, supporting continued liver caution.
  6. [6] Geller SE, Shulman LP, van Breemen RB, et al. Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial. Menopause. 2009;16(6):1156-1166. PMID 19609225 — Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial. Neither black cohosh nor red clover reduced the number of vasomotor symptoms more than placebo, though both were well tolerated with no significant safety concerns over 12 months.

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01 · Clinical Gold StandardRemifemin Menopause Symptoms Relief, 120 Tablets7.9Check price