“Standardized to 2.5% triterpene glycosides”
The label lists 80 mg extract standardized to 2.5% triterpene glycosides (2 mg 27-deoxyactein), the marker actives used in research.
NOW's formula is the cheapest way to get a standardized black cohosh extract (80 mg at 2.5% triterpene glycosides, 2 mg 27-deoxyactein) from a GMP-audited maker. The complication is right on the label: it also contains licorice root and dong quai. Those additions mean any effect can't be attributed to black cohosh alone, and licorice in particular carries its own blood-pressure and potassium cautions. Great actives-per-dollar; less clean as a black cohosh study of one.
Check on AmazonAffiliate link — Super Achiever Club earns a small commission at no extra cost to you.
Read the complete Black Cohosh guide →The black cohosh portion is genuinely standardized — 80 mg extract at 2.5% triterpene glycosides (2 mg 27-deoxyactein), matching the studied actives.
NOW runs an extensive in-house GMP lab program and is Non-GMO, but there is no independent third-party seal on this SKU.
80 mg black cohosh extract at one capsule twice daily is in range, but the added botanicals mean the effective black cohosh exposure isn't the whole story.
Licorice root can raise blood pressure and deplete potassium, and dong quai has anticoagulant and photosensitivity cautions — extra risks layered on top of black cohosh's liver flag.
Around $11 makes it the cheapest standardized extract here, though the added herbs are why it's cheap rather than a pure black cohosh bargain.
“Standardized to 2.5% triterpene glycosides”
The label lists 80 mg extract standardized to 2.5% triterpene glycosides (2 mg 27-deoxyactein), the marker actives used in research.
“Effects come from black cohosh”
The formula also contains licorice and dong quai, so any benefit cannot be attributed to black cohosh alone — a confounded combination.
“Suitable for anyone seeking menopause support”
Licorice can raise blood pressure and lower potassium, and dong quai has anticoagulant cautions, making this combo inappropriate for people with hypertension or on blood thinners.
The black cohosh itself is well-standardized, which is why it ranks above the whole-root picks. But bundling licorice and dong quai turns it into a multi-herb product — you can't isolate black cohosh's contribution, and that's a real drawback if you're testing whether black cohosh works for you.
Glycyrrhizin in licorice root can cause sodium retention, hypertension and hypokalemia with regular use. Anyone with high blood pressure, heart or kidney concerns should treat this combo with more caution than a single-herb black cohosh.
NOW gives you a legitimately standardized black cohosh extract at the lowest price here, but the added licorice and dong quai make it a multi-herb formula with extra cautions rather than a clean single-herb test. Choose it only if you specifically want a combination product and have no blood-pressure or anticoagulant concerns; otherwise a single-herb standardized extract is the wiser buy.
Check NOW Foods on AmazonEfficacy of black cohosh is uncertain and combination products complicate attribution of any observed effect.
Insufficient evidence that black cohosh, alone or combined, outperforms placebo for menopausal symptoms.