Verified
“Synapsa, the future of memory.”
The panel names Synapsa, the trademarked CDRI 08 whole-plant extract, at the 320 mg dose used in the memory trials.
Nootropics Depot Synapsa Bacopa Monnieri 320 mg Review
SAC StudioBest Lab-VerifiedBUY
8.5/10SAC Product Score™
How the score breaks downHide breakdown
SAC Product Score™ — how it breaks down
- Studied Extract & Dose30%9.8
- Standardization Disclosure20%7.8
- Testing & Manufacturing20%9.4
- Formulation & Form15%7.6
- Value15%6.8
Buy it if accredited testing is your first filter; accept the filler and the price
✓ Buy if…
- You want the trial extract with accredited in-house lab testing
- You value a vendor that manufactures and tests under one roof
✗ Skip if…
- You want the bacoside percentage printed
- You want to avoid maltodextrin fillers
Read the full analysis
✓ Also buy if…
- You want a vegetarian capsule
✗ Also skip if…
- You are price-sensitive
Nootropics Depot sells Synapsa, the CDRI 08 whole-plant extract from the memory trials, at the studied 320 mg per capsule, 60 servings, manufactured in its own cGMP facility and tested in its ISO 17025 accredited laboratory. The label lists maltodextrin as a filler, magnesium stearate as a flow agent and vegetable cellulose capsules, and it does not print a bacoside percentage, only the Synapsa trademark.
How we built the SAC Product Score™ — 8.5/10
Studied Extract & Dose30%9.8/10
320 mg Synapsa is the CDRI 08 extract and dose from the twelve-week memory trials; the best trial match on the list, shared with Doctor's Best.
Standardization Disclosure20%7.8/10
The panel names the Synapsa trademark but prints no bacoside percentage; the standard is implied by the extract, not declared.
Testing & Manufacturing20%9.4/10
Manufactured in the vendor's cGMP facility and verified in its ISO 17025 accredited lab, both on the label; the strongest testing credential here.
Formulation & Form15%7.6/10
Vegetable cellulose capsule, but maltodextrin as a filler and magnesium stearate as a flow agent.
Value15%6.8/10
About $0.45 per capsule, the highest cost per day on the list.
The product at a glance
- Form
- Vegetable cellulose capsule
- Serving
- 1 capsule
- Count
- 60 capsules (60 servings)
- Per serving
- 320 mg Synapsa Bacopa monnieri extract (whole plant)
- Standardization
- Not printed on the panel (Synapsa trademark only)
- Other ingredients
- Maltodextrin (filler), magnesium stearate (flow agent), vegetable cellulose (capsules)
- Seals
- cGMP certified facility, ISO 17025 certified lab
- Cost per dose
- ~$0.45 per capsule
Marketing claims vs. reality
Verified
“Verified in our ISO certified lab.”
The label prints ISO 17025 certified lab and cGMP certified facility; both are Nootropics Depot's own operations in Tempe, Arizona.
Partial
“Standardized extract.”
Synapsa is a standardized material, but the panel prints no bacoside percentage; Doctor's Best declares 55 percent for the same extract.
What our test actually found
01Same extract, less on the panel
Synapsa is Synapsa; the material in this capsule should match Doctor's Best. The difference is disclosure: one label prints 55 percent bacosides, the other prints a trademark and a filler.
02You pay for the laboratory
Accredited in-house testing is a real credential for a field-grown herb that can carry heavy metals. At forty-five cents a day it is also the most expensive way to take bacopa on this list.
Pros & cons, no sugar-coating
Pros
- Trial extract at the trial dose
- ISO 17025 accredited in-house lab and cGMP facility on the label
- Vegetarian capsule
Cons
- No bacoside percentage printed
- Maltodextrin filler
- Highest cost per day here
The tested Synapsa, for buyers who read certificates before panels
If who tested it matters most, this is the bacopa to buy. If what the panel commits to matters most, Doctor's Best gives you the same extract with the percentage printed and no filler, for less.
Affiliate link — Super Achiever Club earns a small commission at no extra cost to you.
If this doesn’t fit — try these
Doctor's Best Bacopa with Synapsa
9/10The clinically studied Synapsa extract at 320 mg with the bacoside standardization printed on the panel, in a vegan capsule for a third of a dollar a day — the complete package.
See it on the list →Swanson BaCognize Bacopa
8.7/10The BaCognize clinically studied extract at 250 mg, standardized to 12 percent bacopa glycosides, from a brand with NSF and UL GMP facilities, for sixteen cents a capsule; gelatin capsule, one to three a day.
See it on the list →Nutricost Bacopa Monnieri
8.4/101,000 mg of extract standardized to 50 percent bacosides per two capsules, third-party tested and GMP, in hypromellose capsules for twenty-eight cents; a dose no trial has tested.
See it on the list →Sources & further reading
- Stough C, et al. Psychopharmacology (Berl). 2001;156(4):481-4.Stough C, Lloyd J, Clarke J, Downey LA, Hutchison CW, Rodgers T, Nathan PJ · 2001 · Psychopharmacology · PMID 11498727
The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects
Twelve weeks of 300 mg a day of a standardized Bacopa extract (CDRI 08) improved speed of visual information processing, learning rate and memory consolidation and reduced anxiety in healthy adults; effects were present at twelve weeks, not at five.
- Morgan A, Stevens J. J Altern Complement Med. 2010;16(7):753-9.Morgan A, Stevens J · 2010 · Journal of Alternative and Complementary Medicine · PMID 20590480
Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial
Twelve weeks of 300 mg a day of the CDRI 08 extract improved verbal learning, memory acquisition and delayed recall in adults over 55 compared with placebo, with gastrointestinal effects more common than on placebo.