Nootropics Depot Synapsa Bacopa Monnieri 320 mg Review
#3 of 8 · Best Lab-Verified✓ Label verified · Supplement Facts read Sep 20, 2026Real retailer photo, cut out. Label unedited.
Buy it if accredited testing is your first filter; accept the filler and the price. No other bacopa here is tested in an ISO 17025 accredited lab, and it carries the exact trial extract and dose.
$26-28~$0.45 per capsule (320 mg Synapsa)
Why It Scores 8.5 — And The Label Line Behind Each Number
Studied Extract & Dose
30% of score320 mg Synapsa is the CDRI 08 extract and dose from the twelve-week memory trials; the best trial match on the list, shared with Doctor's Best.
- Per serving
- 320 mg Synapsa Bacopa monnieri extract (whole plant)
Standardization Disclosure
20% of scoreThe panel names the Synapsa trademark but prints no bacoside percentage; the standard is implied by the extract, not declared.
- Standardization
- Not printed on the panel (Synapsa trademark only)
- Seals
- cGMP certified facility, ISO 17025 certified lab
Testing & Manufacturing
20% of scoreManufactured in the vendor's cGMP facility and verified in its ISO 17025 accredited lab, both on the label; the strongest testing credential here.
Formulation & Form
15% of scoreVegetable cellulose capsule, but maltodextrin as a filler and magnesium stearate as a flow agent.
- Form
- Vegetable cellulose capsule
- Other ingredients
- Maltodextrin (filler), magnesium stearate (flow agent), vegetable cellulose (capsules)
Value
15% of scoreAbout $0.45 per capsule, the highest cost per day on the list.
- Serving
- 1 capsule
- Count
- 60 capsules (60 servings)
- Cost per dose
- ~$0.45 per capsule
Label verified. Every figure read from the Supplement Facts photo, Sep 20, 2026.
Marketing Claims Vs. Reality
Synapsa, the future of memory.
The panel names Synapsa, the trademarked CDRI 08 whole-plant extract, at the 320 mg dose used in the memory trials.
Verified in our ISO certified lab.
The label prints ISO 17025 certified lab and cGMP certified facility; both are Nootropics Depot's own operations in Tempe, Arizona.
Standardized extract.
Synapsa is a standardized material, but the panel prints no bacoside percentage; Doctor's Best declares 55 percent for the same extract.
What Our Test Actually Found
Same extract, less on the panel
Synapsa is Synapsa; the material in this capsule should match Doctor's Best. The difference is disclosure: one label prints 55 percent bacosides, the other prints a trademark and a filler.
You pay for the laboratory
Accredited in-house testing is a real credential for a field-grown herb that can carry heavy metals. At forty-five cents a day it is also the most expensive way to take bacopa on this list.
Full analysis: all pros & cons (6), buy if / skip if
- Trial extract at the trial dose
- ISO 17025 accredited in-house lab and cGMP facility on the label
- Vegetarian capsule
- No bacoside percentage printed
- Maltodextrin filler
- Highest cost per day here
- You want the trial extract with accredited in-house lab testing
- You value a vendor that manufactures and tests under one roof
- You want a vegetarian capsule
- You want the bacoside percentage printed
- You want to avoid maltodextrin fillers
- You are price-sensitive
No other bacopa here is tested in an ISO 17025 accredited lab, and it carries the exact trial extract and dose. What holds it back is what is not on the panel: the bacoside percentage, which Doctor's Best prints for the same extract. Add a maltodextrin filler and a per-capsule price forty percent above Doctor's Best and it lands third.
Nootropics Depot sells Synapsa, the CDRI 08 whole-plant extract from the memory trials, at the studied 320 mg per capsule, 60 servings, manufactured in its own cGMP facility and tested in its ISO 17025 accredited laboratory. The label lists maltodextrin as a filler, magnesium stearate as a flow agent and vegetable cellulose capsules, and it does not print a bacoside percentage, only the Synapsa trademark.
The tested Synapsa, for buyers who read certificates before panels
If who tested it matters most, this is the bacopa to buy. If what the panel commits to matters most, Doctor's Best gives you the same extract with the percentage printed and no filler, for less.
If This Doesn’t Fit — Try These
01Doctor's Best Synapsa
If you take bacopa for the memory effect the trials measured, this is the capsule that most closely reproduces them, and it says so on the panel.
02Swanson BaCognize
If the trial extract matters and the price matters more, Swanson's BaCognize gets you both for about twenty cents a day.
04Nutricost 1,000 mg
A well-labelled, tested, vegetarian bacopa whose serving size ignores the trials.
Quick Answers
Is Nootropics Depot Synapsa the same as Doctor's Best Synapsa?
Both name the Synapsa trademark at 320 mg per capsule, so the extract material is the same CDRI 08 whole-plant extract. Doctor's Best prints 55 percent bacosides on its panel; Nootropics Depot prints the trademark only.
Why is there maltodextrin in it?
The panel lists maltodextrin as a filler to bulk the 320 mg extract to capsule size. It is harmless, but it is an ingredient the Doctor's Best capsule does not need.
Sources & Further Reading
2 peer-reviewed sources, each linked to PubMed
- [1] Stough C, et al. Psychopharmacology (Berl). 2001;156(4):481-4. PMID 11498727 — The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Twelve weeks of 300 mg a day of a standardized Bacopa extract (CDRI 08) improved speed of visual information processing, learning rate and memory consolidation and reduced anxiety in healthy adults; effects were present at twelve weeks, not at five.
- [2] Morgan A, Stevens J. J Altern Complement Med. 2010;16(7):753-9. PMID 20590480 — Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. Twelve weeks of 300 mg a day of the CDRI 08 extract improved verbal learning, memory acquisition and delayed recall in adults over 55 compared with placebo, with gastrointestinal effects more common than on placebo.
Affiliate disclosure: every Amazon link uses our Associates tag (superachieverclub-20). We earn a small commission at no cost to you; it funds independent reviews. We never accept payment to change a ranking.