Two capsules for a partial dose
Nested Naturals sells one bottle of 90 vegan capsules, and the label headlines 500mg per serving. The listing directs you to take two capsules once daily, so a single capsule holds 250mg of choline bitartrate, which is roughly 103mg of elemental choline. That makes the labeled serving about 205mg elemental: 48% of the 425mg Adequate Intake for women and 37% of the 550mg for men, with five to six capsules a day needed to cover that Adequate Intake from this product alone.
It scores where it does because one bitartrate above it states its 275mg of elemental choline outright instead of a salt weight and comes from a clinician line whose purity testing is its core selling point (Pure Encapsulations), and another prints the same 500mg figure on a single capsule rather than across two (Solaray, whose panel does not resolve whether that 500mg is elemental choline or salt weight). It also sits under two of the three citicoline picks, which deliver far less elemental choline per milligram but are the better-studied form for the cognitive half of the claim this label makes; the third citicoline pick lands below it.
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Standard choline bitartrate. At ~41% elemental choline it is not a low-density form, sitting on par with Alpha-GPC and well above citicoline per milligram, but it is poorly brain-penetrant and carries no delivery enhancement. It repletes the choline pool for methylation and phospholipid synthesis, which is what the salt is for.
The labeled serving is two capsules holding 500mg of bitartrate, about 205mg elemental choline. The Adequate Intake is 425mg/day for women and 550mg/day for men (PMID 19906248), so the serving covers about 48% of a woman's AI and 37% of a man's. One capsule is roughly 103mg elemental, so covering Adequate Intake from this product alone takes five capsules for a woman and six for a man.
The label carries three seals: VEGAN, NON GMO, and a third reading 3rd Party Certified, Lab Tested for purity & potency. That seal is printed on the product itself rather than living only in listing copy, as this product's own cGMP line does. It is still self-applied: no certifier is named and no certificate of analysis is published, so nothing can be checked at NSF, Informed Sport or any other body. A printed but unattributed seal sits just above the category baseline, which is where a 6.5 lands, better than words in a bullet and short of a credential.
About 103mg elemental choline per capsule and 205mg per serving. Fishy body odor and GI complaints cluster at far higher intakes, and even a six-capsule day stays well under the tolerable upper limit.
No price is knowable for this product right now, so the cost-per-gram half of this criterion could not be scored at all. What is checkable is structure: one bottle, Pack of 1, 90 capsules, 45 labeled servings at two capsules each, so about 45 days at the labeled serving and roughly 15 to 18 days if you dose toward Adequate Intake. The bitartrate at number three prints its 500mg on one capsule, so a labeled serving there is one pill where this takes two. The 5 reflects serving structure and reorder friction only, and is not comparable to the cost-derived Value scores on picks 1 to 3.
“500mg per serving, high potency choline”
The 500mg is the weight of the choline bitartrate salt, and the listing directs you to take 2 capsules once daily, so it is spread across two capsules. Choline is about 41% of bitartrate by weight, making the serving roughly 205mg elemental choline and a capsule roughly 103mg. The label states 500mg per serving and does not state elemental choline anywhere.
“Manufactured in cGMP-certified facilities and third-party tested for consistency and reliability”
The testing half is more than listing copy: the label carries a printed seal reading 3rd Party Certified, Lab Tested for purity & potency. It is still self-applied. No certifier is named, no testing body is identified, and no certificate of analysis is published, so the seal cannot be checked against anything. The cGMP-certified facility line appears only in the listing.
“Supports cognitive performance and liver function”
Intravenous choline reversed hepatic steatosis in parenteral-nutrition patients whose choline was depleted (PMID 7590654), and many adults fall short of the 425-550mg Adequate Intake (PMID 19906248), so the liver half is supported only as deficiency correction, not as a liver benefit from an oral capsule in someone already replete. No source in this review addresses cognitive performance, so that half is not verified.
The label headlines 500MG PER SERVING and the listing instructs you to take 2 capsules once daily. That puts 250mg of bitartrate in a capsule, roughly 103mg of elemental choline, and neither the label nor the listing states the elemental figure at all. Both lean on the salt weight, which is the common industry framing rather than a transparency advantage.
One bottle, Pack of 1, 90 vegan capsules, confirmed on the label. At the labeled two-capsule serving that is 45 servings, so about 45 days. Dosing toward the 425mg (women) to 550mg (men) Adequate Intake from this product alone takes five to six capsules a day, and the same bottle then runs out in roughly 15 to 18 days.
This sits in the same bitartrate class as the clinician-line pick at the top of the list and the one-capsule-labeled pick at number three. It repletes a dietary choline gap and nothing more. The liver evidence behind the class is intravenous choline reversing hepatic steatosis in parenteral-nutrition patients whose choline was depleted (PMID 7590654), which supports correcting a deficiency, not a liver benefit from an oral capsule in someone already replete.
There is nothing wrong with the material. It is a vegan bitartrate that will replete a choline gap, and the label at least prints its testing claim as a seal rather than burying it in a bullet. The problem is arithmetic: the labeled serving spends two capsules out of a 45-serving bottle to deliver about 205mg of elemental choline, and two bitartrates above it cover the same ground with one capsule or with elemental choline stated on the label. Take Pure Encapsulations if you want the elemental figure printed instead of a salt weight, Solaray if you want the 500mg on one capsule instead of two and can accept that its panel does not say whether that figure is elemental or salt, and come here if the 250mg-per-capsule step for titration is the point.
States 275mg of elemental choline outright instead of a salt weight, from a clinician line built on purity testing.
See it on the list →A vegan capsule labeled 500mg. Check the supplement facts panel for whether that figure is elemental choline or salt weight.
See it on the list →Establishes the 425-550mg Adequate Intake and that many adults fall short, supporting basic bitartrate repletion.
Choline repletion reversed deficiency-induced fatty liver, the basis for correcting a dietary gap rather than treating replete NAFLD.
